Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50408983 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_158030 (CHEMBL768621) |
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IC50 | 0.269774±n/a nM |
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Citation | Vieth, M; Cummins, DJ DoMCoSAR: a novel approach for establishing the docking mode that is consistent with the structure-activity relationship. Application to HIV-1 protease inhibitors and VEGF receptor tyrosine kinase inhibitors. J Med Chem43:3020-32 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50408983 |
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n/a |
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Name | BDBM50408983 |
Synonyms: | CHEMBL322897 |
Type | Small organic molecule |
Emp. Form. | C33H39N3O7 |
Mol. Mass. | 589.6787 |
SMILES | CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccc(cc1)[N+]([O-])=O)C(=O)N[C@H]1[C@H](O)Cc2ccccc12 |
Structure |
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