| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-S-isoprenylcysteine O-methyltransferase |
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| Ligand | BDBM50411513 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453677 (CHEMBL885678) |
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| IC50 | 2398.83±n/a nM |
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| Citation |  Leow, JL; Baron, R; Casey, PJ; Go, ML Quantitative structure-activity relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase. Bioorg Med Chem Lett17:1025-32 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-S-isoprenylcysteine O-methyltransferase |
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| Name: | Protein-S-isoprenylcysteine O-methyltransferase |
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| Synonyms: | ICMT | ICMT_HUMAN | Isoprenylcysteine carboxyl methyltransferase | PCCMT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31943.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_956034 |
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| Residue: | 284 |
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| Sequence: | MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYR
PPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLS
LDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVTGLLMVVFGECLRKAAMFT
AGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTV
WRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL
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| BDBM50411513 |
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| n/a |
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| Name | BDBM50411513 |
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| Synonyms: | CHEMBL394211 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29FN2O |
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| Mol. Mass. | 380.4983 |
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| SMILES | CCCCCCCCn1cc(CC(N)=O)c2cc(ccc12)-c1cccc(F)c1 |
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| Structure | 
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