| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|---|
| Ligand | BDBM50411562 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_455564 (CHEMBL903551) |
|---|
| Ki | >30000±n/a nM |
|---|
| Citation |  Mermerian, AH; Case, A; Stein, RL; Cuny, GD Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors. Bioorg Med Chem Lett17:3729-32 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|---|
| Name: | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|---|
| Synonyms: | Neuron cytoplasmic protein 9.5 | PGP 9.5 | PGP9.5 | UCH-L1 | UCHL1 | UCHL1_HUMAN | Ubiquitin thioesterase L1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 24819.03 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_974327 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE
NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE
TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP
FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
|
|
|
|---|
| BDBM50411562 |
|---|
| n/a |
|---|
| Name | BDBM50411562 |
|---|
| Synonyms: | CHEMBL540118 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H8N2O4S |
|---|
| Mol. Mass. | 252.247 |
|---|
| SMILES | CC(=O)c1sc2[nH]c(=O)c(cc2c1N)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
