| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50414932 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_592875 (CHEMBL1046620) |
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| IC50 | 95500±n/a nM |
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| Citation |  Kapanda, CN; Muccioli, GG; Labar, G; Poupaert, JH; Lambert, DM Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors. J Med Chem52:7310-4 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50414932 |
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| n/a |
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| Name | BDBM50414932 |
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| Synonyms: | CHEMBL570228 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H24N4S4 |
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| Mol. Mass. | 364.616 |
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| SMILES | CN1CCN(CC1)C(=S)SCSC(=S)N1CCN(C)CC1 |
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| Structure | 
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