| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50409812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_615773 (CHEMBL1100127) |
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| Ki | 75.86±n/a nM |
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| Citation |  Franchini, S; Prandi, A; Sorbi, C; Tait, A; Baraldi, A; Angeli, P; Buccioni, M; Cilia, A; Poggesi, E; Fossa, P; Brasili, L Discovery of a new series of 5-HT1A receptor agonists. Bioorg Med Chem Lett20:2017-20 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 56862.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35368 |
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| Residue: | 520 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
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| BDBM50409812 |
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| n/a |
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| Name | BDBM50409812 |
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| Synonyms: | CHEMBL1087942 | CHEMBL287686 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H29NO5 |
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| Mol. Mass. | 435.5122 |
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| SMILES | COc1cccc(OC)c1OCCNCC1COC(O1)(c1ccccc1)c1ccccc1 |
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| Structure | 
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