| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 8 |
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| Ligand | BDBM50206509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_836429 (CHEMBL2076869) |
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| Ki | 20000±n/a nM |
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| Citation |  Sugiyama, D; Kusuhara, H; Shitara, Y; Abe, T; Meier, PJ; Sekine, T; Endou, H; Suzuki, H; Sugiyama, Y Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. J Pharmacol Exp Ther298:316-22 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 8 |
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| Name: | Solute carrier family 22 member 8 |
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| Synonyms: | Oat3 | Organic anion transporter 3 | S22A8_RAT | Slc22a8 | rOat3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59199.83 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1482580 |
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| Residue: | 536 |
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| Sequence: | MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPW
VLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNK
LKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFR
FLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQL
TSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFN
LQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQI
IFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKG
CLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGT
TALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG
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| BDBM50206509 |
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| n/a |
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| Name | BDBM50206509 |
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| Synonyms: | 4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfamoyl-benzoic acid anion | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | Benemid | CHEMBL897 | PROBENECID | Probalan |
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| Type | Small organic molecule |
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| Emp. Form. | C13H19NO4S |
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| Mol. Mass. | 285.359 |
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| SMILES | CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O |
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| Structure | 
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