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Target5-hydroxytryptamine receptor 1D
LigandBDBM50422023
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1964 (CHEMBL617569)
IC50 100±n/a nM
Citation Castro, JLBaker, RGuiblin, ARHobbs, SCJenkins, MRRussell, MGBeer, MSStanton, JAScholey, KHargreaves, RJ Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin- 2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor. J Med Chem37:3023-32 (1994) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:5-hydroxytryptamine receptor 1D
Synonyms:5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor
Type:PROTEIN
Mol. Mass.:32680.56
Organism:Sus scrofa
Description:ChEMBL_1963
Residue:291
Sequence:
AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAI
TDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIY
STCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSL
HEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVA
SLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
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  Blast E-value cutoff:
BDBM50422023
n/a
NameBDBM50422023
Synonyms:CHEMBL318571
TypeSmall organic molecule
Emp. Form.C18H28N4O2S
Mol. Mass.364.506
SMILESCC(C)N1CCN(Cc2ccc3[nH]cc(CCN(C)C)c3c2)S1(=O)=O
Structure
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