| Reaction Details |
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 | Report a problem with these data |
| Target | Interstitial collagenase |
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| Ligand | BDBM50101507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458930 (CHEMBL924949) |
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| Ki | 57544±n/a nM |
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| Citation |  Verma, RP; Hansch, C Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioorg Med Chem15:2223-68 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interstitial collagenase |
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| Name: | Interstitial collagenase |
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| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54010.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03956 |
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| Residue: | 469 |
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| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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| BDBM50101507 |
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| n/a |
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| Name | BDBM50101507 |
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| Synonyms: | (R)-3-(((S)-3-cyclohexyl-1-(3-methoxy-3-oxopropylamino)-1-oxopropan-2-yl)carbamoyl)-6-phenylhexanoic acid | (R)-3-[(S)-2-Cyclohexyl-1-(2-methoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-6-phenyl-hexanoic acid | 3-[2-Cyclohexyl-1-(2-methoxycarbonyl-ethylcarbamoyl)-ethylcarbamoyl]-6-phenyl-hexanoic acid | CHEMBL78047 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H38N2O6 |
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| Mol. Mass. | 474.5897 |
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| SMILES | COC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCc1ccccc1)CC(O)=O |
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| Structure | 
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