| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sex hormone-binding globulin |
|---|
| Ligand | BDBM50423507 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_466706 (CHEMBL922711) |
|---|
| Kd | 1148±n/a nM |
|---|
| Citation |  Cherkasov, A; Ban, F; Santos-Filho, O; Thorsteinson, N; Fallahi, M; Hammond, GL An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem51:2047-56 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sex hormone-binding globulin |
|---|
| Name: | Sex hormone-binding globulin |
|---|
| Synonyms: | SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 43780.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_466706 |
|---|
| Residue: | 402 |
|---|
| Sequence: | MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMT
FDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGA
GPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPAS
NLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDI
PQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPL
VLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTS
FCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
|
|
|
|---|
| BDBM50423507 |
|---|
| n/a |
|---|
| Name | BDBM50423507 |
|---|
| Synonyms: | CHEMBL409022 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22O2 |
|---|
| Mol. Mass. | 270.3661 |
|---|
| SMILES | C[C@]12CCC3=C4CCC(=O)C=C4C=C[C@H]3[C@@H]1CC[C@@H]2O |c:4,10,13| |
|---|
| Structure | 
|
|---|
Search and Browse
