| Reaction Details |
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 | Report a problem with these data |
| Target | Sex hormone-binding globulin |
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| Ligand | BDBM51965 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_466706 (CHEMBL922711) |
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| Kd | 1148±n/a nM |
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| Citation |  Cherkasov, A; Ban, F; Santos-Filho, O; Thorsteinson, N; Fallahi, M; Hammond, GL An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem51:2047-56 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sex hormone-binding globulin |
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| Name: | Sex hormone-binding globulin |
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| Synonyms: | SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43780.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_466706 |
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| Residue: | 402 |
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| Sequence: | MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMT
FDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGA
GPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPAS
NLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDI
PQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPL
VLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTS
FCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
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| BDBM51965 |
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| n/a |
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| Name | BDBM51965 |
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| Synonyms: | 3-(2-furanyl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione | 3-(2-furyl)-4-isobutyl-1H-1,2,4-triazole-5-thione | 3-(furan-2-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione | MLS000565615 | SMR000152755 | cid_843761 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13N3OS |
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| Mol. Mass. | 223.295 |
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| SMILES | CC(C)Cn1c(n[nH]c1=S)-c1ccco1 |
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| Structure | 
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