Reaction Details |
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Target | Fatty-acid amide hydrolase 1 [30-579] |
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Ligand | BDBM97458 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_934692 (CHEMBL2318386) |
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IC50 | 4.9±n/a nM |
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Citation | Wilson, AA; Hicks, JW; Sadovski, O; Parkes, J; Tong, J; Houle, S; Fowler, CJ; Vasdev, N Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography. J Med Chem56:201-9 (2013) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Fatty-acid amide hydrolase 1 [30-579] |
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Name: | Fatty-acid amide hydrolase 1 [30-579] |
Synonyms: | Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1 |
Type: | Single-pass membrane protein; homodimer |
Mol. Mass.: | 60474.00 |
Organism: | Rattus norvegicus (rat) |
Description: | P97612 (aa 30-579) |
Residue: | 550 |
Sequence: | RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSG
ELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKG
HDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWK
SSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGC
VYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGY
YETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFL
QNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQH
EIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPV
TTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVE
QLMTPQKQPS
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BDBM97458 |
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n/a |
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Name | BDBM97458 |
Synonyms: | FAAH Inhibitor, 2g |
Type | Small molecule |
Emp. Form. | C19H21NO3 |
Mol. Mass. | 311.3749 |
SMILES | Oc1ccc(OC(=O)NC2CCCCC2)cc1-c1ccccc1 |
Structure |
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