| Reaction Details |
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 | Report a problem with these data |
| Target | SUMO-activating enzyme subunit 1 |
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| Ligand | BDBM50242188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_939698 (CHEMBL2328923) |
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| IC50 | 3000±n/a nM |
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| Citation |  da Silva, SR; Paiva, SL; Lukkarila, JL; Gunning, PT Exploring a new frontier in cancer treatment: targeting the ubiquitin and ubiquitin-like activating enzymes. J Med Chem56:2165-77 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| SUMO-activating enzyme subunit 1 |
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| Name: | SUMO-activating enzyme subunit 1 |
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| Synonyms: | AOS1 | SAE1 | SAE1_HUMAN | SUA1 | SUMO-activating enzyme subunit 1 (SAE1) | SUMO1 activating enzyme subunit 1 | UBLE1A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38440.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_17390638 |
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| Residue: | 346 |
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| Sequence: | MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
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| BDBM50242188 |
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| n/a |
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| Name | BDBM50242188 |
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| Synonyms: | 6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pentadecenyl]salicylic acid | 6-[8(Z)-pentadecatrienyl]salicylic acid | 6-{8(Z)-pentadecenyl}salicylic acid | 6[8'(Z )-pentadecenyl]salicylic acid | Anacardic acid 8'Z-monoene | CHEMBL445177 | Ginkgolic acid C15:1 (1) |
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| Type | Small organic molecule |
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| Emp. Form. | C22H34O3 |
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| Mol. Mass. | 346.5036 |
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| SMILES | CCCCCC\C=C/CCCCCCCc1cccc(O)c1C(O)=O |
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| Structure | 
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