| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-like modifier-activating enzyme ATG7 |
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| Ligand | BDBM50427034 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_939693 (CHEMBL2328918) |
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| IC50 | >10000±n/a nM |
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| Citation |  da Silva, SR; Paiva, SL; Lukkarila, JL; Gunning, PT Exploring a new frontier in cancer treatment: targeting the ubiquitin and ubiquitin-like activating enzymes. J Med Chem56:2165-77 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin-like modifier-activating enzyme ATG7 |
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| Name: | Ubiquitin-like modifier-activating enzyme ATG7 |
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| Synonyms: | APG7-like | APG7L | ATG12-activating enzyme E1 ATG7 | ATG7 | ATG7_HUMAN | Autophagy-related protein 7 | Ubiquitin-activating enzyme E1-like protein | hAGP7 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 77955.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_939703 |
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| Residue: | 703 |
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| Sequence: | MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLP
ARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGT
ALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEAL
ECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQY
PGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPK
AVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLL
LGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADR
LQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRES
RWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLF
ANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEG
GYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYERE
GFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI
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| BDBM50427034 |
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| n/a |
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| Name | BDBM50427034 |
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| Synonyms: | CHEMBL2322194 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N5O4S |
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| Mol. Mass. | 445.535 |
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| SMILES | NS(=O)(=O)OC[C@@H]1C[C@H](C[C@@H]1O)N1CCc2c1ncnc2N[C@H]1CCc2ccccc12 |r| |
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| Structure | 
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