| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium- and chloride-dependent GABA transporter 2 |
|---|
| Ligand | BDBM50427388 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_941201 (CHEMBL2329712) |
|---|
| IC50 | >300000±n/a nM |
|---|
| Citation |  Vogensen, SB; Jørgensen, L; Madsen, KK; Borkar, N; Wellendorph, P; Skovgaard-Petersen, J; Schousboe, A; White, HS; Krogsgaard-Larsen, P; Clausen, RP Selective mGAT2 (BGT-1) GABA uptake inhibitors: design, synthesis, and pharmacological characterization. J Med Chem56:2160-4 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sodium- and chloride-dependent GABA transporter 2 |
|---|
| Name: | Sodium- and chloride-dependent GABA transporter 2 |
|---|
| Synonyms: | GABA transporter | GABA transporter 3 | Gabt2 | Gabt3 | Gat-3 | Gat2 | Gat3 | S6A13_MOUSE | Slc6a13 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 68283.40 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1460089 |
|---|
| Residue: | 602 |
|---|
| Sequence: | MENRASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPY
LCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQM
IVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTSENAT
SPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATF
PYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTAL
GSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFI
AYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLI
LIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNI
EDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALS
SMICIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKNQPEPTAPATPMTSLLRLTELES
NC
|
|
|
|---|
| BDBM50427388 |
|---|
| n/a |
|---|
| Name | BDBM50427388 |
|---|
| Synonyms: | CHEMBL2326024 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H25NO2S2 |
|---|
| Mol. Mass. | 387.559 |
|---|
| SMILES | [#6]-[#7](-[#6]-[#6]\[#6]=[#6](\c1sccc1-[#6])-c1sccc1-[#6])-[#6]-1-[#6]-[#6]-[#6]=[#6]-1-[#6](-[#8])=O |c:23| |
|---|
| Structure | 
|
|---|
Search and Browse
