| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM50428484 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_943453 (CHEMBL2341897) |
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| IC50 | 6.5±n/a nM |
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| Citation |  Wilcken, R; Zimmermann, MO; Lange, A; Joerger, AC; Boeckler, FM Principles and applications of halogen bonding in medicinal chemistry and chemical biology. J Med Chem56:1363-88 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM50428484 |
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| n/a |
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| Name | BDBM50428484 |
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| Synonyms: | CHEMBL2335183 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22BrClFN3O4S |
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| Mol. Mass. | 594.88 |
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| SMILES | Fc1cc(Br)ccc1C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl |r| |
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| Structure | 
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