| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-5 |
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| Ligand | BDBM50432548 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_949940 (CHEMBL2352040) |
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| IC50 | 370±n/a nM |
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| Citation |  Ozcan, S; Kazi, A; Marsilio, F; Fang, B; Guida, WC; Koomen, J; Lawrence, HR; Sebti, SM Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors. J Med Chem56:3783-805 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-5 |
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| Name: | Proteasome subunit beta type-5 |
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| Synonyms: | 20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X |
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| Type: | Protein |
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| Mol. Mass.: | 28480.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 263 |
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| Sequence: | MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
DGWIRVSSDNVADLHEKYSGSTP
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| BDBM50432548 |
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| n/a |
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| Name | BDBM50432548 |
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| Synonyms: | LACTACYSTIN |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N2O7S |
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| Mol. Mass. | 376.425 |
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| SMILES | CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O |r| |
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| Structure | 
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