Reaction Details |
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Target | Tumor necrosis factor receptor superfamily member 6 |
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Ligand | BDBM50439399 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_979855 (CHEMBL2422398) |
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EC50 | 646±n/a nM |
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Citation | Jung, SH; Suh, JH; Kim, EH; Kim, JT; Yoo, SE; Kang, NS The discovery of inhibitors of Fas-mediated cell death pathway using the combined computational method. Bioorg Med Chem Lett23:5155-64 (2013) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Tumor necrosis factor receptor superfamily member 6 |
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Name: | Tumor necrosis factor receptor superfamily member 6 |
Synonyms: | Apo-1 antigen | Apoptosis-mediating surface antigen FAS | Apt1 | CD_antigen=CD95 | FASLG receptor | Fas | TNR6_RAT | Tnfrsf6 |
Type: | PROTEIN |
Mol. Mass.: | 36836.00 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_107643 |
Residue: | 324 |
Sequence: | MLWIMAVLPLVLAGPELNVRMQGTDSIFEGLELKRSVRETDNNCSEGLYQVGPFCCQPCQ
PGERKVKDCTTSGGAPTCHPCTEGEEYTDRKHYSDKCRRCAFCDEGHGLEVETNCTRTQN
TKCRCKENFYCNASLCDHCYHCTSCGLEDILEPCTRTSNTKCKKQSSNYKLLWLLILPGL
AILFVFIYKRYRKRQPGDPESGIPSPESVPMNVSDVNLNKYIWRTAEKMKICDAKKFARQ
HKIPESKIDEIEHNSPQDAAEQKIQLLQCWYQSHGKTGACQALIQGLRKANRCDIAEEIQ
AMVWEDHENSISNSRNENEGQSLE
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BDBM50439399 |
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n/a |
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Name | BDBM50439399 |
Synonyms: | CHEMBL2420421 |
Type | Small organic molecule |
Emp. Form. | C17H13ClN2O4S |
Mol. Mass. | 376.814 |
SMILES | COC(=O)c1oc2cccc(Cl)c2c1NC(=O)CSc1ccccn1 |
Structure |
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