| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoglyceride lipase |
|---|
| Ligand | BDBM50442941 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1276325 (CHEMBL3089787) |
|---|
| IC50 | 400±n/a nM |
|---|
| Citation |  Patel, JZ; Parkkari, T; Laitinen, T; Kaczor, AA; Saario, SM; Savinainen, JR; Navia-Paldanius, D; Cipriano, M; Leppänen, J; Koshevoy, IO; Poso, A; Fowler, CJ; Laitinen, JT; Nevalainen, T Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors. J Med Chem56:8484-96 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoglyceride lipase |
|---|
| Name: | Monoglyceride lipase |
|---|
| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
|---|
| Type: | Hydrolase |
|---|
| Mol. Mass.: | 33264.56 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
|---|
| Residue: | 303 |
|---|
| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
|
|
|
|---|
| BDBM50442941 |
|---|
| n/a |
|---|
| Name | BDBM50442941 |
|---|
| Synonyms: | CHEMBL3087178 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2O4 |
|---|
| Mol. Mass. | 298.2934 |
|---|
| SMILES | COc1nn(Cc2ccc(Oc3ccccc3)cc2)c(=O)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
