| Reaction Details |
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 | Report a problem with these data |
| Target | DNA-directed DNA/RNA polymerase mu |
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| Ligand | BDBM50448689 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1297319 (CHEMBL3132284) |
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| IC50 | >200000±n/a nM |
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| Citation |  Mizushina, Y; Suzuki-Fukudome, H; Takeuchi, T; Takemoto, K; Kuriyama, I; Yoshida, H; Kamisuki, S; Sugawara, F Formosusin A, a novel specific inhibitor of mammalian DNA polymeraseß from the fungus Paecilomyces formosus. Bioorg Med Chem22:1070-6 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA-directed DNA/RNA polymerase mu |
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| Name: | DNA-directed DNA/RNA polymerase mu |
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| Synonyms: | DPOLM_HUMAN | POLM | Pol Mu | Terminal transferase | polmu |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54829.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1297319 |
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| Residue: | 494 |
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| Sequence: | MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLARSKGFRVLD
ACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPVECR
HRLEVAGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFC
RAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLF
TQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQ
VVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLI
LYHQHQHSCCESPTRLAQQSHMDAFERSFCIFRLPQPPGAAVGGSTRPCPSWKAVRVDLV
VAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFR
HLGLEYLPPEQRNA
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| BDBM50448689 |
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| n/a |
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| Name | BDBM50448689 |
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| Synonyms: | CHEMBL3127730 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25NO3 |
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| Mol. Mass. | 291.3853 |
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| SMILES | CCCC[C@@H](O)\C=C(/C)\C=C\C=C/C(=O)N1CCCC1=O |r| |
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| Structure | 
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