| Reaction Details |
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 | Report a problem with these data |
| Target | Indolethylamine N-methyltransferase |
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| Ligand | BDBM50000096 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1333668 (CHEMBL3231054) |
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| IC50 | 6000±n/a nM |
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| Citation |  Rokach, J; Hamel, P; Hunter, NR; Reader, G; Rooney, CS; Anderson, PS; Cragoe, EJ; Mandel, LR Cyclic amidine inhibitors of indolamine N-methyltransferase. J Med Chem22:237-47 (1979) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Indolethylamine N-methyltransferase |
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| Name: | Indolethylamine N-methyltransferase |
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| Synonyms: | Amine N-methyltransferase | Aromatic alkylamine N-methyltransferase | Arylamine N-methyltransferase | INMT | INMT_HUMAN | Indolamine N-methyltransferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28884.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333668 |
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| Residue: | 263 |
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| Sequence: | MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLI
DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN
SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL
CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ
SYSVTNAANNGVCFIVARKKPGP
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| BDBM50000096 |
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| n/a |
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| Name | BDBM50000096 |
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| Synonyms: | CHEMBL3228345 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H14N2O4S |
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| Mol. Mass. | 258.294 |
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| SMILES | OC(=O)\C=C\C(O)=O.C1CN2CCSCC2=N1 |c:15| |
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| Structure | 
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