| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50003621 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1336095 (CHEMBL3240806) |
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| Ki | 42±n/a nM |
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| Citation |  Louvel, J; Guo, D; Agliardi, M; Mocking, TA; Kars, R; Pham, TP; Xia, L; de Vries, H; Brussee, J; Heitman, LH; Ijzerman, AP Agonists for the adenosine A1 receptor with tunable residence time. A Case for nonribose 4-amino-6-aryl-5-cyano-2-thiopyrimidines. J Med Chem57:3213-22 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50003621 |
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| n/a |
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| Name | BDBM50003621 |
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| Synonyms: | CHEMBL3234965 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11N5O2S2 |
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| Mol. Mass. | 369.421 |
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| SMILES | Nc1nc(SCc2cscn2)nc(-c2ccc3OCOc3c2)c1C#N |
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| Structure | 
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