| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium-dependent serotonin transporter |
|---|
| Ligand | BDBM50010305 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1340419 (CHEMBL3253107) |
|---|
| IC50 | 2800±n/a nM |
|---|
| Citation |  Carnmalm, B; Rämsby, S; Renyi, AL; Ross, SB; Ogren, SO Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants. J Med Chem21:78-82 (1978) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sodium-dependent serotonin transporter |
|---|
| Name: | Sodium-dependent serotonin transporter |
|---|
| Synonyms: | 5-HT Transporter | 5HT transporter | 5HTT | Htt | SC6A4_MOUSE | Serotonin transporter | Sert | Slc6a4 | Sodium-dependent serotonin transporter | Solute carrier family 6 member 4 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 70044.92 |
|---|
| Organism: | MOUSE |
|---|
| Description: | 5-HT Transporter SLC6A4 MOUSE::Q60857 |
|---|
| Residue: | 630 |
|---|
| Sequence: | METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAGPGQISNGYSAVPSTSAGDEAP
HSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLP
YTIMAIFGGIPLFYMELALGQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTII
AWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIH
QSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGA
TLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQD
ALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPAS
TFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLT
LTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRIC
WVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLIST
PGTLKERIIKSITPETPTEIPCGDIRMNAV
|
|
|
|---|
| BDBM50010305 |
|---|
| n/a |
|---|
| Name | BDBM50010305 |
|---|
| Synonyms: | CHEMBL3251301 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18ClN |
|---|
| Mol. Mass. | 259.774 |
|---|
| SMILES | Cl.NC1CC(C1)(c1ccccc1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
