| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50010651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1353645 (CHEMBL3271434) |
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| Ki | 248±n/a nM |
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| Citation |  Fujii, H; Hayashida, K; Saitoh, A; Yokoyama, A; Hirayama, S; Iwai, T; Nakata, E; Nemoto, T; Sudo, Y; Uezono, Y; Yamada, M; Nagase, H Novel delta opioid receptor agonists with oxazatricyclodecane structure. ACS Med Chem Lett5:368-72 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50010651 |
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| n/a |
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| Name | BDBM50010651 |
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| Synonyms: | CHEMBL3264741 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H34N2O5 |
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| Mol. Mass. | 502.6014 |
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| SMILES | [H][C@@]12O[C@@]34CC[C@@](O)(N(Cc5ccccc5)C1=O)[C@]2([H])[C@@]31CCN(CC2CC2)[C@]4([H])Cc2ccc(OC)c(O)c12 |r,TLB:24:23:3:39.31.30,THB:7:6:20:1.2| |
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| Structure | 
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