| Reaction Details |
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 | Report a problem with these data |
| Target | Glycine receptor subunit alpha-1 |
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| Ligand | BDBM50016624 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1360626 (CHEMBL3282544) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Hershenson, FM; Prodan, KA; Kochman, RL; Bloss, JL; Mackerer, CR Synthesis of beta-spiro[pyrrolidinoindolines], their binding to the glycine receptor, and in vivo biological acitivity. J Med Chem20:1448-51 (1977) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycine receptor subunit alpha-1 |
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| Name: | Glycine receptor subunit alpha-1 |
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| Synonyms: | GLRA1_RAT | Glra1 | Glycine receptor alpha-1 chain | Glycine receptor subunit alpha-1 | Glycine, non-strychnine | Glycine, strychnine | Glyr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52629.37 |
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| Organism: | RAT |
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| Description: | Glycine, non-strychnine 0 RAT::P07727 |
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| Residue: | 457 |
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| Sequence: | MYSFNTLRFYLWETIVFFSLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF
KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC
IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA
RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA
SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF
QDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPAPAPSKSPEEMRKLFIQRA
KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK
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| BDBM50016624 |
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| n/a |
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| Name | BDBM50016624 |
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| Synonyms: | CHEMBL3274978 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H11NO |
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| Mol. Mass. | 161.2004 |
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| SMILES | CC(=O)N1CCc2ccccc12 |
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| Structure | 
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