| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 5B |
|---|
| Ligand | BDBM50033940 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1436463 (CHEMBL3390778) |
|---|
| Ki | >60000±n/a nM |
|---|
| Citation |  Cumaraswamy, AA; Lewis, AM; Geletu, M; Todic, A; Diaz, DB; Cheng, XR; Brown, CE; Laister, RC; Muench, D; Kerman, K; Grimes, HL; Minden, MD; Gunning, PT Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein. ACS Med Chem Lett5:1202-1206 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Signal transducer and activator of transcription 5B |
|---|
| Name: | Signal transducer and activator of transcription 5B |
|---|
| Synonyms: | STA5B_HUMAN | STAT5B | Signal transducer and activator of transcription 5B | Transcription factor STAT5b (STAT5b) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 89858.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 787 |
|---|
| Sequence: | MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG
GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ
WIPHAQS
|
|
|
|---|
| BDBM50033940 |
|---|
| n/a |
|---|
| Name | BDBM50033940 |
|---|
| Synonyms: | CHEMBL3358600 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H15F5N2O6S2 |
|---|
| Mol. Mass. | 550.476 |
|---|
| SMILES | CN(CC(=O)N(Cc1cccs1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F |
|---|
| Structure | 
|
|---|
Search and Browse
