| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50045307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1458087 (CHEMBL3367650) |
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| IC50 | 1730±n/a nM |
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| Citation |  Li, YJ; Qin, YJ; Makawana, JA; Wang, YT; Zhang, YQ; Zhang, YL; Yang, MR; Jiang, AQ; Zhu, HL Synthesis, biological evaluation and molecular modeling of 1,3,4-thiadiazol-2-amide derivatives as novel antitubulin agents. Bioorg Med Chem22:4312-22 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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| BDBM50045307 |
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| n/a |
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| Name | BDBM50045307 |
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| Synonyms: | CHEMBL3311089 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22BrN3O6S |
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| Mol. Mass. | 536.396 |
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| SMILES | COc1ccc(cc1OC)C(=O)Nc1nnc(\C=C\c2cc(OC)c(OC)c(OC)c2Br)s1 |
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| Structure | 
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