| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50046812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1452788 (CHEMBL3365130) |
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| IC50 | 920±n/a nM |
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| Citation |  Kamal, A; Srinivasa Reddy, T; Polepalli, S; Paidakula, S; Srinivasulu, V; Ganga Reddy, V; Jain, N; Shankaraiah, N Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors. Bioorg Med Chem Lett24:3356-60 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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| BDBM50046812 |
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| n/a |
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| Name | BDBM50046812 |
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| Synonyms: | CHEMBL3309649 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H13F2N3O2 |
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| Mol. Mass. | 401.365 |
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| SMILES | Fc1ccc(cc1F)C1C2=C(COC2=O)Nc2c1c1cccnc1c1ncccc21 |t:10| |
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| Structure | 
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