| Reaction Details |
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 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
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| Ligand | BDBM50051748 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1452145 (CHEMBL3365091) |
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| IC50 | 6.3±n/a nM |
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| Citation |  Cameron, KO; Bhattacharya, SK; Loomis, AK Small molecule ghrelin receptor inverse agonists and antagonists. J Med Chem57:8671-91 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth hormone secretagogue receptor type 1 |
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| Name: | Growth hormone secretagogue receptor type 1 |
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| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR | GHSR_HUMAN | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor | Ghrelin receptor 1a (GHS-R1a) |
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| Type: | Receptor |
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| Mol. Mass.: | 41334.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. |
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| Residue: | 366 |
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| Sequence: | MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
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| BDBM50051748 |
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| n/a |
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| Name | BDBM50051748 |
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| Synonyms: | CHEMBL3358451 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21ClF6N4O |
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| Mol. Mass. | 494.861 |
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| SMILES | CN1CCN(CC1)[C@@H](C(=O)NNc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1Cl |r| |
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| Structure | 
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