| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50055085 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1447961 (CHEMBL3379787) |
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| Ki | 572±n/a nM |
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| Citation |  Squarcialupi, L; Colotta, V; Catarzi, D; Varano, F; Betti, M; Varani, K; Vincenzi, F; Borea, PA; Porta, N; Ciancetta, A; Moro, S 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A1 and A(2A) adenosine receptors. Molecular modeling and pharmacological studies. Eur J Med Chem84:614-27 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50055085 |
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| n/a |
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| Name | BDBM50055085 |
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| Synonyms: | CHEMBL3317560 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N5O |
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| Mol. Mass. | 331.3712 |
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| SMILES | COc1ccccc1Cc1nc(N)c2nn(cc2n1)-c1ccccc1 |
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| Structure | 
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