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TargetSimilar to alpha-tubulin isoform 1
LigandBDBM50056751
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1454104 (CHEMBL3362589)
IC50 67200±n/a nM
Citation Duan, YTSang, YLMakawana, JATeraiya, SBYao, YFTang, DJTao, XXZhu, HL Discovery and molecular modeling of novel 1-indolyl acetate--5-nitroimidazole targeting tubulin polymerization as antiproliferative agents. Eur J Med Chem85:341-51 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Similar to alpha-tubulin isoform 1
Name:Similar to alpha-tubulin isoform 1
Synonyms:Similar to alpha-tubulin isoform 1
Type:PROTEIN
Mol. Mass.:10383.05
Organism:Bos taurus
Description:ChEMBL_104716
Residue:99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50056751
n/a
NameBDBM50056751
Synonyms:CHEMBL3331005
TypeSmall organic molecule
Emp. Form.C23H20N4O4
Mol. Mass.416.4293
SMILESCc1ccccc1\C=C/c1ncc(n1CCOC(=O)c1c[nH]c2ccccc12)[N+]([O-])=O
Structure
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