| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase 1 |
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| Ligand | BDBM50069764 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1469488 (CHEMBL3412285) |
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| IC50 | 888±n/a nM |
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| Citation |  Ndubaku, C; Tsui, V Inhibiting the deubiquitinating enzymes (DUBs). J Med Chem58:1581-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin carboxyl-terminal hydrolase 1 |
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| Name: | Ubiquitin carboxyl-terminal hydrolase 1 |
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| Synonyms: | Deubiquitinating enzyme 1 | UBP1_HUMAN | USP1 | Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48Â | Ubiquitin thioesterase 1 | Ubiquitin-specific-processing protease 1 | hUBP |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88191.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104169 |
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| Residue: | 785 |
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| Sequence: | MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV
VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK
EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR
LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK
EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT
RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK
ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ
IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT
EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL
EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV
TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK
KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD
QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL
FYKKL
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| BDBM50069764 |
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| n/a |
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| Name | BDBM50069764 |
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| Synonyms: | CHEMBL3407501 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H8FNO3 |
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| Mol. Mass. | 293.2487 |
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| SMILES | Fc1ccc(cc1)-c1nc2c(o1)C(=O)c1ccccc1C2=O |
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| Structure | 
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