| Reaction Details |
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 | Report a problem with these data |
| Target | Proteinase-activated receptor 2 |
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| Ligand | BDBM50091326 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1497755 (CHEMBL3583014) |
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| IC50 | 2.0±n/a nM |
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| Citation |  Abdel-Magid, AF Inhibitors of the PAR-2 Signaling Pathway May Treat Pain and Inflammation. ACS Med Chem Lett6:487-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteinase-activated receptor 2 |
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| Name: | Proteinase-activated receptor 2 |
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| Synonyms: | F2RL1 | GPR11 | PAR2 | PAR2_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44152.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1497756 |
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| Residue: | 397 |
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| Sequence: | MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
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| BDBM50091326 |
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| n/a |
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| Name | BDBM50091326 |
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| Synonyms: | CHEMBL3582248 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34FN5O3 |
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| Mol. Mass. | 495.589 |
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| SMILES | CC(C)c1cc(nn2cc(nc12)C(=O)N1CCN(CC1(C)C)C(=O)OC(C)(C)C)-c1ccc(F)cc1 |
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| Structure | 
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