Reaction Details |
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Target | CCR4-NOT transcription complex subunit 7 |
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Ligand | BDBM50119656 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1518114 (CHEMBL3619397) |
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IC50 | 23300±n/a nM |
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Citation | Jadhav, GP; Kaur, I; Maryati, M; Airhihen, B; Fischer, PM; Winkler, GS Discovery, synthesis and biochemical profiling of purine-2,6-dione derivatives as inhibitors of the human poly(A)-selective ribonuclease Caf1. Bioorg Med Chem Lett25:4219-24 (2015) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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CCR4-NOT transcription complex subunit 7 |
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Name: | CCR4-NOT transcription complex subunit 7 |
Synonyms: | BTG1-binding factor 1 | CAF-1 | CAF1 | CCR4-NOT transcription complex subunit 7 | CCR4-associated factor 1 | CNOT7 | CNOT7_HUMAN | Caf1a |
Type: | PROTEIN |
Mol. Mass.: | 32730.66 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_109881 |
Residue: | 285 |
Sequence: | MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY
QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG
IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD
FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK
MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS
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BDBM50119656 |
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n/a |
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Name | BDBM50119656 |
Synonyms: | CHEMBL3616509 |
Type | Small organic molecule |
Emp. Form. | C11H9N5O3 |
Mol. Mass. | 259.2209 |
SMILES | On1c(=O)[nH]c2ncn(Cc3ccncc3)c2c1=O |
Structure |
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