| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM81767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1559800 (CHEMBL3779753) |
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| IC50 | 0.074±n/a nM |
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| Citation |  Waszkielewicz, AM; Gunia-Krzyzak, A; Powroznik, B; Sloczynska, K; Pekala, E; Walczak, M; Bednarski, M; Zeslawska, E; Nitek, W; Marona, H Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. Bioorg Med Chem24:1793-810 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTR1B_RAT | Melatonin receptor 1B | Mt2 | Mtnr1b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40205.08 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_12487 |
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| Residue: | 364 |
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| Sequence: | MPDNSSIANCCAASGLAARPSWPGSAEAEPPETPRAPWVAPMLSTVVIVTTAVDFVGNLL
VILSVLRNRKLRNAGNLFVVNLALADLVVALYPYPLILVAILHDGWVLGEIHCKASAFVM
GLSVIGSVFNITAIAINRYWCICHSATYHRACSQWHAPLYISLIWLLTLVALVPNFFVGS
LEYDPRIYSCTFIQTASTQYTMAVVAIHFLLPIAVVSFCYLRIWILVLQARRKAKAERKL
RLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQIPEGLFVTSYFLAYFN
SCLNAIVYGLLNQNFRREYKRILSALWSTGRCFHDASKCHLTEDLQGPVPPAAMATIPVQ
EGAL
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| BDBM81767 |
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| n/a |
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| Name | BDBM81767 |
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| Synonyms: | 15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646 | Somatostatin-14 |
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| Type | Small organic molecule |
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| Emp. Form. | C76H104N18O19S2 |
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| Mol. Mass. | 1637.878 |
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| SMILES | C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| |
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| Structure | 
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