| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM50159481 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1569186 (CHEMBL3791369) |
|---|
| Ki | 602±n/a nM |
|---|
| Citation |  El Maatougui, A; Azuaje, J; González-Gómez, M; Miguez, G; Crespo, A; Carbajales, C; Escalante, L; García-Mera, X; Gutiérrez-de-Terán, H; Sotelo, E Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes. J Med Chem59:1967-83 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36341.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 332 |
|---|
| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
|
|
|
|---|
| BDBM50159481 |
|---|
| n/a |
|---|
| Name | BDBM50159481 |
|---|
| Synonyms: | CHEMBL3787123 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14N4O3 |
|---|
| Mol. Mass. | 274.2753 |
|---|
| SMILES | CCOC(=O)C1=C(C)Nc2ncnn2C1c1ccoc1 |c:5| |
|---|
| Structure | 
|
|---|
Search and Browse
