| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50439270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1573765 (CHEMBL3802949) |
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| IC50 | 60±n/a nM |
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| Citation |  Zetterberg, F; Svensson, P State of affairs: Design and structure-activity relationships of reversible P2Y12 receptor antagonists. Bioorg Med Chem Lett26:2739-2754 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50439270 |
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| n/a |
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| Name | BDBM50439270 |
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| Synonyms: | CHEMBL2419497 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClN4O5S2 |
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| Mol. Mass. | 468.934 |
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| SMILES | CCOC(=O)c1cc(C#N)c(nc1C)N1CC(C1)C(=O)NS(=O)(=O)c1ccc(Cl)s1 |
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| Structure | 
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