| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50055094 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1575929 (CHEMBL3802552) |
|---|
| Ki | 55±n/a nM |
|---|
| Citation |  Squarcialupi, L; Falsini, M; Catarzi, D; Varano, F; Betti, M; Varani, K; Vincenzi, F; Dal Ben, D; Lambertucci, C; Volpini, R; Colotta, V Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A1 and A2A adenosine receptors. Bioorg Med Chem24:2794-808 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44716.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29274 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
|
|
|
|---|
| BDBM50055094 |
|---|
| n/a |
|---|
| Name | BDBM50055094 |
|---|
| Synonyms: | CHEMBL3317574 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H19N5 |
|---|
| Mol. Mass. | 329.3984 |
|---|
| SMILES | Nc1nc(CCCc2ccccc2)nc2cn(nc12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
