| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 1B1 |
|---|
| Ligand | BDBM50145829 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1583531 (CHEMBL3815618) |
|---|
| IC50 | >120000±n/a nM |
|---|
| Citation |  Lee, D; Perez, P; Jackson, W; Chin, T; Galbreath, M; Fronczek, FR; Isovitsch, R; Iimoto, DS Aryl morpholino triazenes inhibit cytochrome P450 1A1 and 1B1. Bioorg Med Chem Lett26:3243-3247 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 1B1 |
|---|
| Name: | Cytochrome P450 1B1 |
|---|
| Synonyms: | CP1B1_HUMAN | CYP1B1 | CYPIB1 | Cytochrome P450 1B1 (CYP1B1) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60861.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1474523 |
|---|
| Residue: | 543 |
|---|
| Sequence: | MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLI
GNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAF
ASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVAL
LVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSL
VDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSA
EKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAEL
DQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVV
FVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQL
FLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKE
TCQ
|
|
|
|---|
| BDBM50145829 |
|---|
| n/a |
|---|
| Name | BDBM50145829 |
|---|
| Synonyms: | 4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL542 | PABA | p-Aminobenzoesaeure | p-aminobenzoic acid | para-aminobenzoic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H7NO2 |
|---|
| Mol. Mass. | 137.136 |
|---|
| SMILES | Nc1ccc(cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
