| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50179399 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1583800 |
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| IC50 | 42500±n/a nM |
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| Citation |  Khan, FA; Patil, RH; Shinde, DB; Sangshetti, JN Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction. Bioorg Med Chem24:3456-63 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | 3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2 |
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| Type: | n/a |
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| Mol. Mass.: | 16901.39 |
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| Organism: | Escherichia coli |
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| Description: | n/a |
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| Residue: | 150 |
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| Sequence: | MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIV
IDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFE
LEADGLLAICIGLRLGNGKYCTLRLFFNQV
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| BDBM50179399 |
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| n/a |
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| Name | BDBM50179399 |
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| Synonyms: | CHEMBL3814600 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22FN3O |
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| Mol. Mass. | 387.4494 |
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| SMILES | Fc1cc(NCc2ccc(cc2)-c2ccccc2C#N)ccc1N1CCOCC1 |
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| Structure | 
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