Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Peptide deformylase |
---|
Ligand | BDBM50179409 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1583800 (CHEMBL3815887) |
---|
IC50 | 15660±n/a nM |
---|
Citation | Khan, FA; Patil, RH; Shinde, DB; Sangshetti, JN Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction. Bioorg Med Chem24:3456-63 (2016) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Peptide deformylase |
---|
Name: | Peptide deformylase |
Synonyms: | 3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2 |
Type: | n/a |
Mol. Mass.: | 16901.39 |
Organism: | Escherichia coli |
Description: | n/a |
Residue: | 150 |
Sequence: | MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIV
IDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFE
LEADGLLAICIGLRLGNGKYCTLRLFFNQV
|
|
|
BDBM50179409 |
---|
n/a |
---|
Name | BDBM50179409 |
Synonyms: | CHEMBL3814475 |
Type | Small organic molecule |
Emp. Form. | C20H15N3O2 |
Mol. Mass. | 329.352 |
SMILES | [O-][N+](=O)c1ccccc1NCc1ccc(cc1)-c1ccccc1C#N |
Structure |
|