Reaction Details |
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Target | Peptide deformylase |
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Ligand | BDBM50179428 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1583800 (CHEMBL3815887) |
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IC50 | 51160±n/a nM |
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Citation | Khan, FA; Patil, RH; Shinde, DB; Sangshetti, JN Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction. Bioorg Med Chem24:3456-63 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptide deformylase |
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Name: | Peptide deformylase |
Synonyms: | 3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2 |
Type: | n/a |
Mol. Mass.: | 16901.39 |
Organism: | Escherichia coli |
Description: | n/a |
Residue: | 150 |
Sequence: | MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIV
IDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFE
LEADGLLAICIGLRLGNGKYCTLRLFFNQV
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BDBM50179428 |
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n/a |
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Name | BDBM50179428 |
Synonyms: | CHEMBL3814974 |
Type | Small organic molecule |
Emp. Form. | C21H16N2O2 |
Mol. Mass. | 328.3639 |
SMILES | OC(=O)c1ccc(NCc2ccc(cc2)-c2ccccc2C#N)cc1 |
Structure |
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