| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cholinesterase |
|---|
| Ligand | BDBM50190651 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1612309 (CHEMBL3854109) |
|---|
| IC50 | >200000±n/a nM |
|---|
| Citation |  Ortiz, JE; Pigni, NB; Andujar, SA; Roitman, G; Suvire, FD; Enriz, RD; Tapia, A; Bastida, J; Feresin, GE Alkaloids from Hippeastrum argentinum and Their Cholinesterase-Inhibitory Activities: An in Vitro and in Silico Study. J Nat Prod79:1241-8 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cholinesterase |
|---|
| Name: | Cholinesterase |
|---|
| Synonyms: | BCHE | Butyrylcholinesterase (BuChE) | CHLE_HORSE | Cholinesterase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 65643.35 |
|---|
| Organism: | Equus caballus (Horse) |
|---|
| Description: | P81908 |
|---|
| Residue: | 574 |
|---|
| Sequence: | EEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATK
YANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQT
GTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQK
NIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEAR
NRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLT
DMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPR
VSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYY
FEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNP
NGTQNNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAE
REWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF
|
|
|
|---|
| BDBM50190651 |
|---|
| n/a |
|---|
| Name | BDBM50190651 |
|---|
| Synonyms: | CHEMBL3956367 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19NO4 |
|---|
| Mol. Mass. | 301.3371 |
|---|
| SMILES | [H][C@]12CN(Cc3cc4OCOc4cc13)[C@@]1([H])[C@H](OC)[C@@H](O)CC=C21 |r,t:25| |
|---|
| Structure | 
|
|---|
Search and Browse
