| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50196400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1618421 (CHEMBL3860590) |
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| IC50 | 617±n/a nM |
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| Citation |  Azevedo, CM; Watterson, KR; Wargent, ET; Hansen, SV; Hudson, BD; Kepczynska, MA; Dunlop, J; Shimpukade, B; Christiansen, E; Milligan, G; Stocker, CJ; Ulven, T Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity. J Med Chem59:8868-8878 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50196400 |
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| n/a |
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| Name | BDBM50196400 |
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| Synonyms: | CHEMBL3979588 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13FN2O3S |
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| Mol. Mass. | 380.392 |
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| SMILES | Fc1cc(Oc2ccc(cc2)C#N)cc(c1)N1Cc2ccccc2S1(=O)=O |
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| Structure | 
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