| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM50197882 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1620067 (CHEMBL3862350) |
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| IC50 | 2020±n/a nM |
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| Citation |  Simões, CJV; Almeida, ZL; Costa, D; Jesus, CSH; Cardoso, AL; Almeida, MR; Saraiva, MJ; Pinho E Melo, TMVD; Brito, RMM A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition. Eur J Med Chem121:823-840 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM50197882 |
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| n/a |
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| Name | BDBM50197882 |
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| Synonyms: | CHEMBL3959466 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H9ClO4 |
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| Mol. Mass. | 252.65 |
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| SMILES | Cc1c(\C=C\c2ccc(Cl)o2)occ1C(O)=O |
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| Structure | 
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