Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 1A | ||
| Ligand | BDBM50207155 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1630051 (CHEMBL3872757) | ||
| Ki | 2.9±n/a nM | ||
| Citation |  Chen, XW; Sun, YY; Fu, L; Li, JQ Synthesis and pharmacological characterization of novel N-(trans-4-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)cyclohexyl)amides as potential multireceptor atypical antipsychotics. Eur J Med Chem123:332-353 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 1A | |||
| Name: | 5-hydroxytryptamine receptor 1A | ||
| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A | ||
| Type: | n/a | ||
| Mol. Mass.: | 46122.49 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 422 | ||
| Sequence: |
| ||
| BDBM50207155 | |||
| n/a | |||
| Name | BDBM50207155 | ||
| Synonyms: | CHEMBL3895540 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H32N4O2S3 | ||
| Mol. Mass. | 504.731 | ||
| SMILES | CN([C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)S(=O)(=O)c1cccs1 |r,wU:2.1,wD:5.5,(23.14,-23.94,;23.62,-22.48,;25.13,-22.16,;25.61,-20.7,;27.11,-20.38,;28.14,-21.52,;29.64,-21.2,;30.67,-22.35,;32.18,-22.03,;33.21,-23.17,;34.72,-22.85,;35.19,-21.39,;34.16,-20.24,;32.66,-20.56,;36.7,-21.06,;37.33,-19.66,;38.86,-19.82,;39.18,-21.32,;40.51,-22.1,;40.51,-23.63,;39.18,-24.41,;37.84,-23.63,;37.84,-22.1,;27.67,-22.98,;26.16,-23.31,;22.59,-21.33,;21.1,-20.94,;21.51,-22.42,;23.07,-19.87,;22.16,-18.63,;23.07,-17.38,;24.53,-17.86,;24.53,-19.4,)| | ||
| Structure | 
| ||