| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK3 |
|---|
| Ligand | BDBM50208715 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1633068 (CHEMBL3875860) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Labrière, C; Lozach, O; Blairvacq, M; Meijer, L; Guillou, C Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors. Eur J Med Chem124:920-934 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity protein kinase CLK3 |
|---|
| Name: | Dual specificity protein kinase CLK3 |
|---|
| Synonyms: | CDC2-like kinase 3 (CLK3) | CLK3 | CLK3_HUMAN | Dual specificity protein kinase CLK3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 73570.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 638 |
|---|
| Sequence: | MPVLSARRRELADHAGSGRRSGPSPTARSGPHLSALRAQPARAAHLSGRGTYVRRDTAGG
GPGQARPLGPPGTSLLGRGARRSGEGWCPGAFESGARAARPPSRVEPRLATAASREGAGL
PRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEG
RLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHR
RRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWL
QERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKD
KENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALR
FLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHT
TIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGP
IPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRM
LEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
|
|
|
|---|
| BDBM50208715 |
|---|
| n/a |
|---|
| Name | BDBM50208715 |
|---|
| Synonyms: | CHEMBL3884570 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H12N4O |
|---|
| Mol. Mass. | 276.2927 |
|---|
| SMILES | COc1ccc2c(c[nH]c2n1)C(=C\c1cccnc1)\C#N |
|---|
| Structure | 
|
|---|
Search and Browse
