| Reaction Details |
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 | Report a problem with these data |
| Target | Transglycosylase |
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| Ligand | BDBM50217266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153093 |
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| IC50 | 1060±n/a nM |
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| Citation |  Greenlee, ML; Laub, JB; Rouen, GP; DiNinno, F; Hammond, ML; Huber, JL; Sundelof, JG; Hammond, GG Dicationic 2-fluorenonylcarbapenems: potent anti-MRS agents with improved solubility and pharmacokinetic properties. Bioorg Med Chem Lett9:3225-30 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Transglycosylase |
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| Name: | Transglycosylase |
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| Synonyms: | B9Z08_11275 | EP54_02360 | EQ90_10185 | HMPREF3211_02644 | PBP2 | Penicillin binding protein 2 | Transglycosylase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 80439.51 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_103873 |
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| Residue: | 727 |
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| Sequence: | MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFFVVLLLGILLFAYYAWK
APAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFYE
HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQ
EYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY
DHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDLKANLVNRTPEERQNIDTNQDSEYN
SYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTNMDKDVQKTLQNDVDNGSFYKNKDQQV
GATILDSKTGGLVAISGGRDFKDVVNRNQATDPHPTGSSLKPFLAYGPAIENMKWATNHA
IQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKFAA
KLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEY
DHTSHKAMSDYTAYMLAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLP
DNAAKDVWINGFTPQYTMSVWMGFSKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDG
EDFKRPSSVSGSIPSINVSGSQDNNTTNRSTHGGSDTSANSSGTAQSNNNTRSQQSRNSG
GLTGIFN
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| BDBM50217266 |
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| n/a |
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| Name | BDBM50217266 |
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| Synonyms: | CHEMBL422426 | L-695256 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H23N3O5 |
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| Mol. Mass. | 469.4886 |
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| SMILES | [H][C@]12CC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C([O-])=O)c1ccc2C(=O)c3cc(C[n+]4ccn(C)c4)ccc3-c2c1 |c:3| |
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| Structure | 
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