Reaction Details | |||
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Target | Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor | ||
Ligand | BDBM50228202 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_36478 (CHEMBL651547) | ||
Ki | 9310±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor | |||
Name: | Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor | ||
Synonyms: | Angiotensin II receptor | Type-1A/Type-1B/Type-2 angiotensin II receptor | ||
Type: | n/a | ||
Mol. Mass.: | n/a | ||
Description: | ASSAY_ID of ChEMBL is 36477 | ||
Components: | This complex has 3 components. | ||
Component 1 | |||
Name: | Type-1 angiotensin II receptor B | ||
Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 40929.44 | ||
Organism: | RAT | ||
Description: | Angiotensin II AT1B 0 RAT::P29089 | ||
Residue: | 359 | ||
Sequence: |
| ||
Component 2 | |||
Name: | Type-2 angiotensin II receptor | ||
Synonyms: | AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 41346.62 | ||
Organism: | RAT | ||
Description: | Angiotensin II AT2 0 0::P35351 | ||
Residue: | 363 | ||
Sequence: |
| ||
Component 3 | |||
Name: | Type-1 angiotensin II receptor A | ||
Synonyms: | AGTRA_RAT | ANGIOTENSIN AT1 | Agtr1 | Agtr1a | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | At1a | Type-1A angiotensin II receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 40910.53 | ||
Organism: | RAT | ||
Description: | ANGIOTENSIN AT1 AGTR1 RAT::P25095 | ||
Residue: | 359 | ||
Sequence: |
| ||
BDBM50228202 | |||
n/a | |||
Name | BDBM50228202 | ||
Synonyms: | CHEMBL368638 | ||
Type | Small organic molecule | ||
Emp. Form. | C39H61N13O8 | ||
Mol. Mass. | 839.9839 | ||
SMILES | CNCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@@H]1C(N)=O |wU:36.36,17.16,56.59,wD:43.43,24.23,6.5,(1.06,-8.48,;1.83,-7.17,;3.16,-6.41,;4.5,-7.17,;4.5,-8.7,;5.8,-6.41,;7.14,-7.17,;7.14,-8.7,;8.45,-9.47,;8.45,-10.99,;9.78,-11.78,;9.78,-13.31,;11.12,-14.07,;8.45,-14.07,;8.45,-6.41,;8.45,-4.88,;9.78,-7.17,;11.12,-6.41,;11.12,-4.88,;12.46,-4.11,;9.78,-4.11,;12.46,-7.17,;12.46,-8.7,;13.76,-6.41,;15.1,-7.17,;15.1,-8.7,;16.44,-9.47,;17.74,-8.7,;19.08,-9.47,;19.08,-10.99,;20.42,-11.78,;17.74,-11.78,;16.44,-10.99,;16.44,-6.41,;16.44,-4.88,;17.74,-7.17,;19.08,-6.41,;19.08,-4.88,;20.42,-4.11,;17.74,-4.11,;20.42,-7.17,;20.42,-8.7,;21.72,-6.41,;23.06,-7.17,;23.06,-8.7,;23.63,-10.17,;23.19,-11.76,;24.62,-12.62,;25.89,-11.52,;25.18,-10.17,;24.4,-6.41,;24.4,-4.88,;25.7,-7.17,;25.86,-8.7,;27.36,-9.02,;28.15,-7.68,;27.1,-6.54,;27.42,-5.04,;26.31,-4.02,;28.89,-4.58,)| | ||
Structure | ![]() |