Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50041237 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1660368 (CHEMBL4009980) |
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Ki | 0.500000±n/a nM |
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Citation | Glennon, RA The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The"Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. J Med Chem60:2605-2628 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50041237 |
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n/a |
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Name | BDBM50041237 |
Synonyms: | ((R)-1-Methyl-2-phenyl-ethyl)-(5-phenyl-pentyl)-amine | CHEMBL280160 |
Type | Small organic molecule |
Emp. Form. | C20H27N |
Mol. Mass. | 281.4351 |
SMILES | C[C@H](Cc1ccccc1)NCCCCCc1ccccc1 |
Structure |
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