| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuromedin-U receptor 1 |
|---|
| Ligand | BDBM50049425 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1664053 |
|---|
| EC50 | 0.590000±n/a nM |
|---|
| Citation |  Kanematsu-Yamaki, Y; Nishizawa, N; Kaisho, T; Nagai, H; Mochida, T; Asakawa, T; Inooka, H; Dote, K; Fujita, H; Matsumiya, K; Hirabayashi, H; Sakamoto, J; Ohtaki, T; Takekawa, S; Asami, T Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2-selective PEGylated Peptide. J Med Chem60:6089-6097 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuromedin-U receptor 1 |
|---|
| Name: | Neuromedin-U receptor 1 |
|---|
| Synonyms: | G-protein coupled receptor 66 | G-protein coupled receptor FM-3 | Gpr66 | NMU-R1 | NMUR1_MOUSE | Nmur1 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 47951.94 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | n/a |
|---|
| Residue: | 428 |
|---|
| Sequence: | MTPPCLNCSIFPGALSPNASRSPLVCNISEFKWPYQPEDLNLTDEALRLKYLGPQQMKQF
VPICVTYLLIFVVGTLGNGLTCTVILRNKTMRTPTNFYLFSLAVSDMLVLLVGLPLELYE
MQQNYPFQLGASACYFRILLLETVCLASVLNVTALSVERYVAVVRPLQAKSVMTRAHVRR
MVGAIWVLATLFSLPNTSLHGLSQLTVPCRGPVPDSAICSLVGPMDFYKLVVLTTALLFF
CLPMVTISVLYLLIGLRLRRERMLLQVEVKGRKTAATQETSHRRIQLQDRGRRQVTKMLF
ALVVVFGICWAPFHADRIMWSLVYGHSTEGLHLAYQCVHIASGIFFYLGSAANPVLYSLM
STRFRETFLQALGLGTQCCHRRQPYHGSHNHIRLTTGSTLCDVGHRNSRDEPLAVNEDPG
CQQETDPS
|
|
|
|---|
| BDBM50049425 |
|---|
| n/a |
|---|
| Name | BDBM50049425 |
|---|
| Synonyms: | CHEMBL3356083 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C54H78N16O10 |
|---|
| Mol. Mass. | 1111.2983 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
